多糖類氨基甲酸酯衍生物的合成研究.pdf

1、哈爾濱工程大學(xué)碩士學(xué)位論文多糖類氨基甲酸酯衍生物的合成研究姓名：劉占勇申請學(xué)位級別：碩士專業(yè)：應(yīng)用化學(xué)指導(dǎo)教師：劉文彬20090601哈爾濱工程大學(xué)碩十學(xué)位論文ABSTRACTManyderivativesofpolysaceharidessuchascellulose，amylose，chitosanhavebeenexaminedaSchiralstationaryphases(CSPs)forenantioseparationby

2、HPLCAmongthem，cellulosederivatives，especiallyphenylcarbamatederivatives，havebeenmostextensivelystudiedandmanyempiricalcorrelationshavebeenestablishedbetweenthephysicalorchemicalpropertiesandenantiomerrecognitionabilities

3、ofCSPsTheperformancequalitiesofCSPsintermsofrecognitionandselectivechiralretentionareattheheartoftheseseparationtechniquesSo，thisfieldremainsoneofthemostexcitingintheseparationsciences強emainworksofthethesisaleasfollows：T

4、hedevelopmentofthechiralstationaryandtheapplicationofthecellulosederivativesaschiralstationaryphasesinhighperformanceliquidchromatographywerereviewedTheseparationmechanismbasedonthechiralstationaryphaseWasdiscussedSynthe

5、sisofisocyanateswithtriphosgene9Hfluoren2ylisocyanate，4bromophenylisocyanate，4chlorphenylisocyanateetc，werepreparedfromtriphosgeneandcorrespondingaminesunderanitrogenatmosphere，thesyntheticconditionssuchasreagentformular

6、eactiontemperatureandreactiontimewereoptimizedTheirstructureswereconfirmedbyFTIR(KBrbackground)andNM＆CelluloseandamylosederivativeswhichcouldbeusedasCSPsweresynthesizedfromcellulose(amylose)andcorrespondingisocyanatesbas