吡唑基苯并噁唑衍生物的合成與除草活性研究.pdf

1、大連理工大學(xué)碩士學(xué)位論文吡唑基苯并噁唑衍生物的合成與除草活性研究姓名：薛娜申請學(xué)位級別：碩士專業(yè)：物理化學(xué)指導(dǎo)教師：曲景平周宇涵20080609吡唑基苯并嗯唑衍生物的合成與除草活性研究SynthesesandHerbicidalActivityofPyrazolylBenzoxazoleDerivativesAbstractInhancementofmankind’Senvironmentalconcepthadimpartedthed

2、evelopmentofnovelpesticidesanewthemefeatured“superhi曲effectivity，lowtoxicity，nopollution”Pmtoporphyrinogenoxidaseinhibitorherbicideisbecomingahotpointofnovelherbicidedevelopmentbecauseitinhibitstheenzymecatalysingthesynt

3、hesisofchlorophylinplantcell，allowsgoodtoxicityselectivitybetweenplantsandanimals，andischaracterizedbyhi曲effectivity，lowtoxicityandmoderateresidueSinceChina’Sreformandopenup，thepesticideindustryinChinahasgreatlybeendevel

4、opedTherearemorethan2000manufacturingfactoriesandalmost300kindsofpesticidesareproducedIn2007，thetotalamountofpesticideproductionoutputranksthefirstworldwideHowever，themakeupofpesticideproductsinChinaisnotSOrationalInsect

5、icidestaketoolargeproportionwhilethedevelopmentofherbicidesarefarbehindtheleveloftheworld，amongwhichtwomuchhightoxicityandlowactivityproducts，tobephasedout，arestillprevailinginthemarketFurthermore，thepesticidesproducedin

6、chinaarenumerouslyimitationofthosepreviouslydevelopedinlackofindependentintellectualpropertyrightsAimedattheproblemdiscussedabove，inthefieldofcreatingnewprotoporphyrinogenoxidaseinhibitorherbicide謝thanessentialstructureo

7、fsubstitutedpyrazolylbenzoxazoles，thefollowingworkisaccomplishedinthispaperUsing4fluorophenolasstartingmaterial，viaaserialofreactionsincludedchloridation，acylation，condensation，ringclosure，methylation，nitration，andSOon，2

8、1substitutedpyrazolylbenzoxazolederivativesarepreparedAllthestructuresareconfirmedbyH1NMR，MSandelementanalysis，andareneverreportedinanyliteraturePreliminarybioassayshowsthatmostsubstitutedpyrazolylbenzoxazolederivativese